Healthy Lifespan and Hypoxic-Hyperoxic Preconditioning
Oxygen waves and healthy longevity, episode 1.2
People · Scientific Advisor
Arkadi Prokopov
Scientific Advisor
Dr Arkadi Prokopov is a physician in integrative medicine, a specialist in hypoxic training and an expert in mitochondrial medicine, with more than 30 years of experience in intermittent hypoxic-hyperoxic training (IHHT).
30+ years of IHHTMITOPRO protocolMitochondrial medicine2 patents
Biography
About
Dr Prokopov developed MITOPRO (MiTochondria Optimization PROtocol), a highly individualised protocol of hypoxic training. He is the author of many scientific and popular works on biomedicine and on the use of interval hypoxic training in sport and biogerontology, and holds two patents in the field.
He graduated in internal medicine from the First Moscow Medical Institute named after I. M. Sechenov in 1980. After working as a practising physician, he spent more than ten years as a research fellow at a biomedical research institute, studying the prevention and treatment of stress-related conditions in professional divers, cosmonauts and military personnel, and prepared a dissertation on the subject.
In 1994 he began practising medicine in Germany, and from 2000 to 2004 he worked in the United States as an expert in IHHT. Over more than 15 years he has worked with elite athletes on both sides of the Atlantic.
Since 2008 he has conducted clinical research in integrative and mitochondrial medicine on Mallorca, Spain, where he offers consultations and trains physicians and practitioners in his method, with seminars in Mallorca and Moscow. His clients have included elite athletes, business leaders and well-known public figures.
30+YearsOf experience with IHHT
15+YearsWorking with elite athletes
2PatentsOn hypoxic training
MITOPRO
MiTochondria Optimization PROtocol
His own method of hypoxic training
MITOPRO is a highly individualised protocol of intermittent hypoxic-hyperoxic training. Short periods of breathing oxygen-reduced air alternate with oxygen-rich recovery: a mild, controlled stress that prompts mitochondria to adapt and renew.
- Tailored to each person, not a fixed programme
- Built on more than 30 years of clinical use of IHHT
- Taught to physicians and practitioners through seminars in Mallorca and Moscow
IHHTMethodIntermittent hypoxic-hyperoxic training
2008SinceClinical research on Mallorca
1
HypoxiaBrief low-oxygen intervals2
HyperoxiaOxygen-rich recovery3
AdaptationMitochondria renew4
IndividualisedTailored to each personCareer
From diving and space medicine to mitochondrial medicine
Four decades of clinical and research work across Russia, Germany, the United States and Spain.
1980
MoscowGraduates in internal medicine, First Moscow Medical Institute
1980s–90s
Research fellowStress-related conditions in divers, cosmonauts and military
1994
GermanyPractising physician
2000–04
United StatesExpert in IHHT
2008–now
Mallorca, SpainClinical research and physician training
Video
Exploring new frontiers in human performance and longevity
These techniques work, but you don’t have to take our word for it: see the evidence for yourself.
The method, practised by its author
Dr Prokopov played a major role in developing this technology and studying its safety and use in conditions including Lyme disease, diabetes, Alzheimer’s and autism. He has also tested it on himself.
Watch the video ↗
Staying Healthy in Space
Talk, September 2021
Book
Undoing Lyme Disease
How to Make Your Mitochondria Fight Lyme Borreliosis by Surfing Oxygen Waves
Why would a biogerontologist, mitochondrial researcher and diving physician write a book on Lyme borreliosis? To help readers take a proactive role in their own health. Dr Prokopov has used the method he describes for more than 30 years, for himself, his family and his patients, and explains simply but in detail why it works against Lyme disease and its co-infections.
Rather than asking for blind obedience, the book invites readers to build their own individualised plan from the modules that suit them best.
View the book ↗Scientific papers
Selected publications
Research on hypoxic preconditioning, mitochondrial rejuvenation and brain health.
Intermittent Hypoxia and Health: From Evolutionary Aspects to Mitochondria Rejuvenation
Examines mitochondrial ageing as a gradual loss of energy reserves and stress resistance, and why keeping mitochondria in a vital state is key to reducing age-related disease.
Read the paper ↗A Case of Recovery From Dementia Following Rejuvenative Treatment
Describes a patient born in 1931 who recovered from a year of mental decline after rejuvenative treatment.
Read the paper ↗Affordable Rejuvenation: A Prototype Facility In Action
Presents a working prototype of the periodic rejuvenation and maintenance centres envisaged by the SENS (Strategies for Engineered Negligible Senescence) agenda.
Read the paper ↗Exploring Overlooked Natural Mitochondria-Rejuvenative Intervention: The Puzzle of Bowhead Whales and Naked Mole Rats
Looks to two exceptionally long-lived species for clues to natural, mitochondria-rejuvenating interventions.
Read the paper ↗Utility of Hypoxic Preconditioning in the Treatment of Dementia
Makes the case for hypoxic preconditioning in dementia care, building on evidence that physical activity lowers dementia risk and that the brain stays adaptable into late adulthood.
Read the paper ↗Metabolic Neuroimaging using Direct Current Potential
Shows how a reduced cortical direct-current potential reflects lowered brain metabolism in brain injury, stroke, neurodegenerative disease and dementia.
Read the paper ↗At the foundation
Role and contribution
Scientific Advisor
Advises the Foundation on hypoxic training and mitochondrial medicine.
Habitat design
Leads the scientific and medical design of the Foundation’s undersea and off-world habitats programme.
Conference speaker
Spoke at the Foundation’s 2021 conference on mitochondria research for human longevity and space medicine.
Online
Follow Dr Prokopov’s work
Talks, protocol updates and research news.