The UK's oldest longevity charity · since 2008
Prevent · Restore · Preserve
We use the power of science to alleviate suffering through preventive and restorative medicine — advancing the scientific R&D and social-impact work behind practical longevity, mitochondrial medicine and global health.
Our scientific priorities
The Foundation's restored research agenda concentrates on the intersection of hypoxia, mitochondrial medicine and extreme environments — the science underlying practical longevity and its translation to global health.
Priority 01
The intersection of hypoxic conditioning, mitochondrial resilience and extreme environments — from deep-space radiation countermeasures to self-sustaining undersea and off-world habitats, and their translation to terrestrial longevity.
Priority 02
Comprehensive research on intermittent hypoxic and hypoxic–hyperoxic training and hyperbaric oxygen therapy — devices, protocols and their compositions, with dedicated testing of machines and protocols against a validated evidence base.
Priority 03
A multi-university UAE veterinary trial testing whether IHHT, HBOT and their combination improve healthspan, biological-age and fertility biomarkers in aged dogs and cats — the translational bridge between human and companion-animal longevity.
The unifying thread
One scientific throughline connects every priority: controlled oxygen modulation and mitochondrial hormesis. The same mechanisms that rejuvenate mitochondria on Earth protect crews from cumulative radiation injury in space and extend healthspan in companion animals.
Active research programs
Space · Terrestrial
A time-critical integrated hypoxic radioprotection framework treating habitat oxygen partial pressure as an active design variable — a two-level architecture of moderate habitat hypoxia plus monitored deeper excursions during solar-particle-event sheltering. A missing environmental layer for Mars-class missions, and a translational bridge to terrestrial longevity.
Devices · Protocols
Comprehensive study, testing and optimization of intermittent hypoxic–hyperoxic training machines and protocols — mapping their composition, pros and cons, and the routes to improvement. Includes the advanced H5I2T protocol for high-performance neuroenhancement, and a clinician AI co-pilot pre-loaded with thousands of protocol variations.
Veterinary · Translational
A multi-university UAE veterinary clinical-trial platform testing IHHT, HBOT and HBOT+IHHT across ~10 breeds each of aged dogs and cats — measuring biological-age, healthspan, mitochondrial and fertility biomarkers. Conducted with the Oxy Wave Foundation and university PIs under veterinary ethics oversight.
Habitats · Existential Risk
Self-sustaining, HealthTech-integrated modular habitats for undersea, lunar and Martian environments — mitigating existential climate risk while providing an ideal controlled environment for mitochondrial-medicine and longevity technologies. Scientific and medical design led by Arkadi Prokopov.
Our ecosystem
Strategic research partner. Oxy Wave operationalizes IHHT and structured breathwork into deployable programs; BGRF is its scientific anchor for translational aging and population-level work.
See the Science ↗Our science underpins the translation of mitochondrial-medicine protocols to hard-to-treat conditions — Lyme, Long COVID, Autism, Alzheimer's, Diabetes and more.
Explore GHC ↗The device, protocol and habitat programs that turn our research into real-world oxygen-modulation infrastructure — from clinics to undersea and off-world settings.
View Programs ↗History & scope of activities
Founded in 2008.
Launched as a UK non-profit by prominent longevity scientists.
Jointly secured the WHO-approved ageing-related extension code in 2018 — a world-first.
Authored the first comprehensive overviews of the entire global longevity industry.
Partnerships & co-foundations include ATLAS (UK), VETEK (Israel), the Canadian Longevity Association, Longevity International Association (Geneva) — plus conferences on mitochondrial research, practical longevity and space medicine.
In 2018, together with the International Longevity Alliance, the Foundation successfully contributed to the addition of a new World Health Organization-approved extension code — XT9T, ‘ageing-related’ — during the ICD-11 revision. We were the first group to bring the classification of ageing this close to formal recognition.
Our 2018 Oncotarget paper set out a roadmap for enhancing human radioresistance for deep-space exploration and colonisation — converging radiobiology and biogerontology.
A large international collaboration bringing together radiobiology, gerontology and space-medicine groups to define the interventions that could make humans meaningfully more radioresistant.
The Foundation convenes and speaks at conferences bringing longevity science together with space medicine and mitochondrial research.
A two-day virtual conference bringing mitochondrial research into direct contact with space medicine — the clearest expression of the Foundation’s scientific throughline.
People
Entrepreneur, venture philanthropist and investor, involved in longevity and aging research since 2014.
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Coordinates research direction, publications and programme delivery.
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Trustee since 2025, after more than a decade supporting the Foundation's policy work as a volunteer.
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Pioneer of hypoxic training in mitochondria medicine and creator of the MITOPRO protocol.
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